As a matter of fact, the cultivation of the domesticated grape began 6,000–8,000 years ago in the Near East. Grapes are an ellipsoid-shaped type of fruit that grow in clusters, and can be crimson, black, dark blue, yellow, green, orange, and pink. Besides, they can be classified as either table or wine grapes, based on their intended method of consumption. Nutritionally, a diet that is rich in fruits and vegetables has been linked to a reduced risk of various conditions, including heart disease, diabetes, cancer, and obesity. In addition, grapes contain powerful antioxidants known as polyphenols, which are thought to have anti-inflammatory and antioxidant properties.