Aspirin is without a doubt one of the most widely used medications globally. This medication is typically used to reduce pain, fever, or inflammation, such as Kawasaki disease, pericarditis, and rheumatic fever. When given shortly after a heart attack, Aspirin can also decrease the risk of death, not to mention that it is also used to help prevent further heart attacks in people at high risk. As a matter of fact, humans have been using a precursor to aspirin found in leaves from the willow tree for at least 2,400 years. However, the aspirin we know came into being in the late 1890s in the form of acetylsalicylic acid when chemist Felix Hoffmann at Bayer in Germany used it to alleviate his father's rheumatism. It is worth noting that Aspirin should not be taken by people who are allergic to ibuprofen or naproxen, or who have salicylate intolerance. Besides, caution should be exercised in those with asthma. Owing to the drug’s effect on the stomach lining, it is recommended that people with peptic ulcers, mild diabetes, or gastritis seek medical advice before using aspirin. Furthermore, Aspirin is not recommended in the last part of pregnancy, nor is it recommended in children with infections because of the risk of Reye syndrome