Approved for medical use in 1978, Desmopressin is a medication used to treat diabetes insipidus, bedwetting, hemophilia A, von Willebrand disease, and high blood urea levels. Technically, this drug works by reducing the amount of urine produced in the body at night by the kidneys – A process that helps fill the bladder with less urine during the night. For the treatment of diabetes insipidus, take Desmopressin by mouth, usually 2 to 3 times a day or as directed by your doctor. For the treatment of bedwetting, take this drug by mouth, usually once a day at bedtime. Bear in mind that children should limit the fluids they drink after dinner, especially 1 hour before the Desmopressin dose until the next morning, or at least 8 hours after the dose. And if your child wakes up during the night, limit the amount that he or she drinks. It is worth noting that Desmopressin can cause headaches, diarrhea, and low blood sodium. In fact, the low blood sodium may cause seizures. Remember that Desmopressin should not be used in people with significant kidney problems or low blood sodium. Fortunately, though, this medication appears to be safe to use during pregnancy.