Dapsone, which was first used in 1945, is an antibiotic commonly used for the treatment of leprosy, and also for the treatment and prevention of pneumocystis pneumonia. This medication is also used to prevent toxoplasmosis in those who have poor immune function, not to mention that it has been used for acne, dermatitis herpetiformis, and various other skin conditions. It is worth noting that Dapsone works by decreasing swelling (inflammation) and stopping the growth of bacteria. Bear in mind that you should take this antibiotic as directed for as long as it has been prescribed, even if you are feeling better. Plus, Dapsone may be taken with food or on an empty stomach. You can, however, take it with food if stomach upset occurs. As far as the severe side effects of this medication are concerned, they may include a decrease in blood cells, red blood cell breakdown especially in those with glucose-6-phosphate dehydrogenase deficiency, or hypersensitivity. Dapsone has other side effects that need to be taken into consideration such as nausea, loss of appetite, liver inflammation and a number of types of skin rashes. While the safety of use during pregnancy is not entirely clear some physicians recommend that it be continued in those with leprosy.