Discovered in 1939, Griseofulvin is an antifungal medication used to treat fungal infections that can affect different parts of your body such as your hair, nails, and skin. Basically, this drug works by binding to a part of the fungus causing the infection in your body, thereby stopping the fungus from multiplying. In addition, Griseofulvin also prevents fungus from spreading to new cells – A process that eventually kills off the infection. It is worth noting that the side effects of this drug include allergic reactions, nausea, diarrhea, headache, trouble sleeping, and feeling tired. Bear in mind that Griseofulvin is not recommended in people with liver failure or porphyria. Besides, the use of this drug during or in the months before pregnancy may result in harm to the baby. When it comes to its use, Griseofulvin is best taken with or after meals, especially fatty ones (e.g., whole milk or ice cream). This, of course, lessens possible stomach upset and helps to clear up the infection by helping your body absorb the medicine better. However, if you are on a low-fat diet, check with your doctor before using this medication.