Hyaluronate is actually similar to a substance that occurs naturally in joints and that helps joints work properly by acting like a lubricant and shock absorber. Plus, this medicine is injected directly into the knee to relieve pain caused by osteoarthritis. In fact, Sodium hyaluronate is usually given when other arthritis medications have not been effective. Remember that you should avoid jogging, strenuous activity, or high-impact sports such as soccer or tennis for at least 48 hours after your injection. Also avoid weight-bearing activity or standing for longer than 1 hour at a time. It is worth noting that Sodium hyaluronate is not approved for use by anyone younger than 21 years old. However, you should tell your doctor, regardless of your age, if you have ever has blood clots or circulation problems in your legs, or if you’ve ever had an allergy to birds, feathers, or egg products. As a matter of fact, it is not known whether sodium hyaluronate will harm an unborn baby. You need to tell your doctor, nonetheless, if you are pregnant before using this medication.