Patented in 1969, Fenofibrate is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. This medication basically works by increasing the natural substance (enzyme) that breaks down fats in the blood. However, it does not appear to reduce the risk of heart disease or death. As for the side effects of Fenofibrate, they include liver problems, breathing problems, abdominal pain, muscle problems, and nausea. In addition, this drug has other serious side effects such as toxic epidermal necrolysis, rhabdomyolysis, gallstones, blood clots, and pancreatitis. Bear in mind that the use of Fenofibrate during pregnancy and breastfeeding is not recommended. And since it is less well absorbed from an empty stomach, Fenofibrate capsules should always be taken with food.