Hydrocortisone, which was patented in 1936, is a topical corticosteroid used to treat mild inflammatory skin conditions, commonly referred to as dermatitis. In fact, Hydrocortisone creams and ointments are available in most countries without prescription in strengths ranging from 0.05% to 2.5% with stronger forms available by prescription only. Bear in mind that covering the skin after applying this cream increases the absorption and effect. As a matter of fact, Hydrocortisone is not particularly useful for the treatment of hives since they are caused by histamines rather than by skin inflammation. In addition, this lotion cannot be used to treat acne and can, in fact, make the condition worse. Hydrocortisone should also NOT be used to treat a skin infection or any broken skin, including blisters, boils, ulcers, or chancre sores. While side effects are rare if a hydrocortisone product is used as directed, they can happen. Therefore, you need to stop the medication and contact your doctor if any of these occur: irregular heartbeats, blurred vision, insomnia, puffy face, blistering, or if your skin condition gets worse. Remember that Hydrocortisone is not recommended if you are breastfeeding. In addition, it should not be used extensively on pregnant patients, in large amounts or for extended periods of time.