Also known as Oxpentifylline, Pentoxifylline has been used widely in the treatment of intermittent claudication (i.e. muscle pain in people with peripheral artery disease), which is a prevalent condition in the elderly population. It is worth noting that Pentoxifylline is used to improve blood flow in patients with circulation problems to reduce aching, cramping, and tiredness in the hands and feet. Besides, it works by decreasing the thickness of blood, thereby allowing it to flow more easily, especially in the small blood vessels of the hands and feet. When it comes to the side effects of this drug, they include belching, bloating, stomach discomfort or upset, nausea, vomiting, indigestion, dizziness, and flushing. Pentoxifylline also has other side effects that are rather uncommon and rare such as angina, palpitations, hypersensitivity, itchiness, rash, hives, bleeding, hallucinations, arrhythmias, and aseptic meningitis. Since there are no controlled data in human pregnancy, this medication is only recommended for use during pregnancy when benefit outweighs risk. Also bear in mind that Pentoxifylline should be taken with meals to lessen the chance of stomach upset. Taking an antacid with the medicine may also help.