Azficel-T is approved by the FDA for the treatment of what is usually referred to as “smile lines”, which in turn are the wrinkles that are seen from the sides of the nose to the corners of the mouth. Remember to tell your doctor about your allergies before using this product in order to make sure that it will be 100% safe and effective. And if you are pregnant, you should also consult them beforehand, considering there are still no adequate studies in pregnant women who have used Azficel-T. As for the common side effects, they include swelling and redness of the skin at the injection site. Irritation and itching at the injection site are deemed less common. Don’t forget to contact your healthcare provider if you experience headache, jaw pain, pimples, or toothache. Bear in mind that you will be given azficel-t by a trained doctor, and they will give it to you through a small needle placed into your “smile lines”.