Brexpiprazole, which is sold under the brand name “Rexulti”, is an antipsychotic drug indicated for the treatment of the symptoms of schizophrenia. Besides, it is also used with other medications to treat major depressive disorder. According to drugs.com, Brexpiprazole works by “altering chemicals in the brain that can lead to schizophrenia or depression”. Among the things that you need to take into consideration before using this drug is the fact that those who took part in clinical trials were advised to avoid grapefruit, Seville oranges and related citruses. Therefore, for your own safety, you should not consume them, too, while taking Brexpiprazole. Plus, if you are treated for dementia-related psychosis, you must not use the medication in question. Bear in mind that having suicidal thoughts is not particularly uncommon among those who take Brexpiprazole. Therefore, seeking medical advice is definitely recommended as soon as you start noticing any change in your mood. It is worth noting that “taking antipsychotic medicine in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn.”(drugs.com). So, if you get pregnant, you need to tell your doctor right away. As for the common side effects of Brexpiprazole, they include weight gain and restlessness. In addition, this drug has other side effects that are more serious and require immediate medical help such as uncontrollable facial movements, seizures, high blood sugar, and signs of a blood clot, among others. Remember that you can take Brexpiprazole with or without food.