Bivalirudin (or Angiomax) is a synthetic peptide that is used as a blood-thinner during certain heart blood vessel surgeries, mainly in patients with severe chest pain or unstable angina “undergoing percutaneous transluminal coronary angioplasty”. Among the things that you should tell your doctor about before using Bivalirudin is if you have bleeding problems, or if you have an active bleeding. You must also tell them about the other drugs that you may be using to make sure that they won’t interact with this anticoagulant. It is worth noting that Bivalirudin “is given as a shot into a vein or into a vein nonstop for a period of time”. As for the side effects that can occur, some of them are listed on xlist.com as follows: back/pelvis pain, nausea, vomiting, stomach pain, restlessness, nervousness, anxiety, headache and fever. Remember to tell your doctor if you are pregnant /breastfeeding to get their professional advice on whether or not you should use this medicine.