canagliflozin

Canagliflozin, which was approved for medical use in 2013, is an oral anti-diabetic medicine that helps control blood sugar levels in patients with type 2 diabetes. This drug is typically used together with exercise and diet, although it is not recommended in type 1 diabetes. Canagliflozin basically reduces the re-absorption of glucose from renal tubules, leading to more excretion of glucose in urine. Remember that you should not use canagliflozin if you have severe kidney disease or if you are on dialysis. In fact, this medication may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage. As for the side effects of canagliflozin, they include vaginal yeast infections, nausea, constipation, and urinary tract infections. Additionally, this drug has more serious side effects such as low blood sugar, Fournier's gangrene, leg amputation, kidney problems, high blood potassium, and low blood pressure. Bear in mind that using canagliflozin during pregnancy and breastfeeding is not recommended. On a side note, this drug should be taken at the same time every day, preferably before the first meal of the day.