Cholera vaccines, which were first developed in the late 1800s, are vaccines that are effective at preventing cholera. For the first six months after vaccination, they actually provide about 85 percent protection, which decreases to 50 percent or 62 percent during the first year. However, the level of protection decreases to less than 50 percent after two years. It is worth noting that the Cholera vaccine works by exposing the patient to a small dose of live cholera bacteria, which causes the body to develop immunity to the disease. This vaccine will not, however, treat an active infection that has already developed in the body. Bear in mind that two or three doses are typically recommended with the oral vaccine. When it comes to the side effects, mild abdominal pain or diarrhea may occur. Fortunately, Cholera vaccines are safe in pregnancy and in those with poor immune function.