Eflornithine, which came into medical use in 1990, is a topical medication indicated for the treatment of African trypanosomiasis. Although it does not permanently remove facial hair, Eflornithine is also used to reduce excessive hair growth on the face in women, and it does so by “interfering with a chemical in hair follicles under the skin.” Bear in mind that you should not use this medication if you tried it before and ended up having an allergic reaction to it. In addition, using Eflornithine during pregnancy or breastfeeding is not recommended without first consulting a doctor as it is unknown whether this drug could harm an unborn/nursing baby. As for the common side effects, drugs.com lists the following: temporary rash, acne on the skin, skin dryness, and headache. Don’t forget to get immediate medical help when you experience severe irritation, or redness around your hair follicles.