Suramin, which was made as early as 1916, is indicated for the treatment of African sleeping sickness and river blindness. According to drugs.com, this medication works “by causing the parasites to lose energy, which causes their death.” Bear in mind that the most common side effects that usually happen as a result of using Suramin include nausea, diarrhea, vomiting, and abdominal pain. Tingling sensations in the skin, limb numbness, and palm pain are also widely reported. There are also other side effects that are rather less common than the previous ones, and they include extreme fatigue, and mouth sores. Difficulty breathing caused by hypersensitivity reactions, decreased blood pressure, unusual bleeding and rapid heart rate are thankfully one of the few rare side effects of this medication. It is worth noting that pregnant women should not use Suramin if they have a chronic nonfatal condition such as onchocerciasis. It is only recommended if there are no suitable alternatives available. Remember to follow your doctor's advice on how you should use this medicine in case you want to know if you should take it on an empty stomach or after a meal.