Estradiol ring, which is available under the name Estring, is indicated for the treatment of moderate to severe menopausal changes that occur after menopause, whether in or around the vaginal area. It treats, for instance, dryness, burning, and itching of the vaginal area. Besides, it also treats urgency or irritation with urination, and pain during sexual intercourse. According to drugs.com, Estradiol vaginal rings contain Estradiol, which in turn is a form of estrogen necessary for many processes in the body. So, what Estradiol basically does is release estrogen so as to be absorbed through the skin of the vaginal wall. Bear in mind that you should not use this vaginal ring if you have unexplained vaginal bleeding, or if you’ve ever experienced heart problems. It is also not recommended that you use it during pregnancy. So, make sure you tell your doctor if you are expecting a baby. As far as the common side effects are concerned, they include breast pain, headache, nausea, stomach cramps, and vaginal itching. You should, however, call your doctor right away if you experience any of the following side effects: memory problems, lump in your breast, pelvic pain, or sudden weakness.